Diagnosis and treatment of cervical lymph metastasis carcinoma from unknown primary tumor / 中华放射肿瘤学杂志

ABSTRACT

Cervical lymph metastasis carcinoma from unknown primary tumor (CCUP) accounts for 3% to 5% of all malignant tumors of head and neck. With the development of PET-CT, molecular pathology, endoscopy and other auxiliary examinations and the advancement of radiotherapy technology, the diagnostic and treatment levels of CCUP have been gradually improved. Surgery and radiotherapy are the most important treatment methods of CCUP. However, due to its low incidence and heterogeneity, prospective clinical trial data are still lacking. Hence, the optimal therapy of CCUP remains highly controversial. In this article, research progresses on the diagnosis and treatment of CCUP in recent years were reviewed.