Post-operative pancreatic fistula and acute pancreatitis following pancreaticoduodenectomy / 中华肝胆外科杂志

ABSTRACT

Postoperative pancreatic fistula (POPF) is a common complication and the main leading cause of death after pancreaticoduodenectomy (PD). In recent years, with the deepening of people's understanding of acute pancreatitis (AP) after pancreatic surgery, more and more evidence shows that AP is another common complication which is different from POPF after PD. AP is an independent risk factor for the occurrence and development of POPF, and is closely related to serious complications such as infection and death. The establishment of the concept of AP after PD makes people have a more comprehensive understanding of the pathophysiological changes of residual pancreatic tissue in the early stage after PD, and further understanding of the occurrence and development mechanism of POPF, and have more thoughts on the prevention and treatment measures of AP and POPF after PD, which will further enhance clinical management level and safety after PD.