A Case of Systematized Nevus Sebaceous / 대한피부과학회지

ABSTRACT

A patient with nevus sebaceous showing linear or wide distribution can present with a triad of nevus sebaceous, seizures, and mental retardation. Most of those cases are classified as sebaceous nevus syndrome. Ophthalmological, skeletal, and other abnormalities may also be present. A male weighing 3,580 g was born at the gestational age of 38 weeks after a normal pregnancy. He was referred to the dermatologic department on the first day of life. He presented with yellow-orange and verrucous plaques on both sides of the temporal areas, face, neck, upper and lower extremities, and trunk. Skin biopsy specimens were taken from the scalp and right lower leg. Histologically, both specimens showed sebaceous gland hyperplasia, absence of mature hair follicles, infundibular cystic structures, and apocrine glands. Brain magnetic resonance imaging, transthoracic echocardiography, abdomen ultrasonography, and routine laboratory investigations were performed and showed nonspecific findings. The patient did not show seizure activity at 19 days of observation, and he is now on close observation. We herein report a very rare case of systematized nevus sebaceous presenting at birth.