Progress in omics research and preclinical models of gallbladder cancer / 中华外科杂志
Chinese Journal of Surgery
; (12): 260-264, 2023.
Article
em Zh
| WPRIM
| ID: wpr-970189
Biblioteca responsável:
WPRO
ABSTRACT
Gallbladder cancer(GBC)is one common type of bile tract cancers with poor prognosis. This review summarizes the recent development of studies about somatic mutation, molecular subtype, microenvironment heterogeneity, organoid, orthotopic model, patient-derived xenograft and clinical translation on GBC in aspects of genomic,transcriptome,single cell omics and clinical translation. We expect this review will provide new ideas on dissecting molecular mechanisms underlying the development and emerging chemoresistance of GBC following therapy and promote GBC precision medicine.
Texto completo:
1
Índice:
WPRIM
Assunto principal:
Prognóstico
/
Microambiente Tumoral
/
Neoplasias da Vesícula Biliar
Limite:
Humans
Idioma:
Zh
Revista:
Chinese Journal of Surgery
Ano de publicação:
2023
Tipo de documento:
Article