Research progress on chemical constituents and pharmacological effects of Glechomae Herba and prediction of its Q-markers / 中国中药杂志
China Journal of Chinese Materia Medica
; (24): 2041-2058, 2023.
Article
em Zh
| WPRIM
| ID: wpr-981336
Biblioteca responsável:
WPRO
ABSTRACT
Glechomae Herba, the dried aerial part of Glechoma longituba(Labiatae), has the effects of promoting urination, draining dampness, and relieving stranguria. It has received wide attention in recent years owing to the satisfactory efficacy on lithiasis. Amid the in-depth chemical and pharmacological research, it has been found that Glechomae Herba has antibacterial, anti-inflammatory, antioxidant, antithrombotic, hepatoprotective, cholagogic, antitumor, hypoglycemic, and lipid-lowering effects. The main chemical constituents are volatile oils, flavonoids, terpenoids, phenylpropanoids, and organic acids. This paper summarized the chemical constituents and pharmacological effects of Glechomae Herba. Based on genetic relationship of plants, the characteristics, efficacy, and pharmacokinetics of the chemical constituents, and the potential of these constituents as quality markers(Q-markers), it was summed up that ursolic acid, caffeic acid, rosmarinic acid, luteolin-7-O-diglucuronide, apigenin, apigenin-7-O-diglucuronide, apigetrin, and glechone can be the candidate Q-markers of Glechomae Herba.
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Texto completo:
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Índice:
WPRIM
Assunto principal:
Flavonoides
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Medicamentos de Ervas Chinesas
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Extratos Vegetais
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Lamiaceae
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Apigenina
Idioma:
Zh
Revista:
China Journal of Chinese Materia Medica
Ano de publicação:
2023
Tipo de documento:
Article