Research Progress of Exosomes and Their Forensic Significance / 法医学杂志
Journal of Forensic Medicine
; (6): 754-762, 2022.
Article
em En
| WPRIM
| ID: wpr-984168
Biblioteca responsável:
WPRO
ABSTRACT
Exosomes are membranous tiny vesicles secreted by cells, which are widely found in the extracellular matrix and various body fluids and carry a variety of biologically functional molecules such as proteins, lipids, messenger RNA (mRNA) and microRNA (miRNA). Exosomes not only play important biological roles in the field of immunology and oncology, but also have potential application value in the field of forensic medicine. This article reviews the discovery, production and degeneration mechanism, biological functions, isolation and identification methods of exosomes, summarizes the research on exosomes and their significance in the field of forensic science, and discusses their applications in body fluid identification, individual identification, postmortem interval estimation to provide ideas for the application of exosomes in forensic work.
Palavras-chave
Texto completo:
1
Índice:
WPRIM
Assunto principal:
RNA Mensageiro
/
MicroRNAs
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Ciências Forenses
/
Exossomos
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Medicina Legal
Idioma:
En
Revista:
Journal of Forensic Medicine
Ano de publicação:
2022
Tipo de documento:
Article