The alternative splicing & expression of fibronectin IIIcs segment and its relationship with wound healing / 法医学杂志
Journal of Forensic Medicine
; (6): 245-248, 2001.
Article
em Zh
| WPRIM
| ID: wpr-984804
Biblioteca responsável:
WPRO
ABSTRACT
Fibronectin is an important large adhesive glycoprotein of the extracellular matrix, which is alternatively spliced in three regions, designated EIIIA, EIIIB and IIIcs respectively. IIIcs contains two binding domains for a variety of cell surface and extracellular ligands. Through this multiplicity of adhesive activities, IIIcs can fulfill key roles in a broad spectrum of physiological processes, such as cell spreading and migration, differentiation and embryogenesis, wound healing, malignant transformation and metastasis, etc. Here, we will discuss the structure, biological property, and function of IIIcs splicing variants and its forensic applications.
Texto completo:
1
Índice:
WPRIM
Assunto principal:
Cicatrização
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Fibronectinas
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Processamento Alternativo
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Medicina Legal
Limite:
Animals
/
Humans
Idioma:
Zh
Revista:
Journal of Forensic Medicine
Ano de publicação:
2001
Tipo de documento:
Article