Research progress of soluble growth stimulating gene 2 protein in cardiovascular disease / 中国基层医药
Chinese Journal of Primary Medicine and Pharmacy
; (12): 1276-1280, 2023.
Article
em Zh
| WPRIM
| ID: wpr-991892
Biblioteca responsável:
WPRO
ABSTRACT
Growth stimulating gene 2 (ST2) protein is a member of the interleukin-1 receptor family. It is mainly divided into a soluble secreted form sST2 and a transmembrane form ST2L. sST2 is a decoy receptor that competitively binds to interleukin-33 to block the interleukin-33/ST2L signaling pathway, worsening myocardial hypertrophy, fibrosis, and ventricular dysfunction. Measuring sST2 is of important value for diagnosis and/or prognosis evaluation of cardiovascular diseases. This paper mainly reviews the research progress in the relationship between cardiovascular diseases such as heart failure, coronary heart disease, hypertension, atrial fibrillation, myocarditis, cardiomyopathy, acute aortic dissection, and pulmonary hypertension, and sST2.
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1
Índice:
WPRIM
Idioma:
Zh
Revista:
Chinese Journal of Primary Medicine and Pharmacy
Ano de publicação:
2023
Tipo de documento:
Article