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Interaction of Biomphalaria cells in primary cultures with Schistosoma mansoni sporocysts
Silva-Neto, Aristeu; Fonseca, Cristhiane Oliveira da; Silva, Luciana Maria; Coelho, Paulo Marcos Zech; Fortes-Dias, Consuelo Latorre.
Affiliation
  • Silva-Neto, Aristeu; Fundação Oswaldo Cruz. Instituto René Rachou. Belo Horizonte. BR
  • Fonseca, Cristhiane Oliveira da; Fundação Oswaldo Cruz. Instituto René Rachou. Belo Horizonte. BR
  • Silva, Luciana Maria; Fundação Ezequiel Dias. Diretoria de Pesquisa e Desenvolvimento. Belo Horizonte. BR
  • Coelho, Paulo Marcos Zech; Fundação Oswaldo Cruz. Instituto René Rachou. Belo Horizonte. BR
  • Fortes-Dias, Consuelo Latorre; Fundação Ezequiel Dias. Diretoria de Pesquisa e Desenvolvimento. Belo Horizonte. BR
Rev. Soc. Bras. Med. Trop ; Rev. Soc. Bras. Med. Trop;53: e20200257, 2020. graf
Article в En | SES-SP, ColecionaSUS, LILACS | ID: biblio-1136878
Ответственная библиотека: BR1.1
ABSTRACT
Abstract

INTRODUCTION:

Biomphalaria snails may display varying levels of susceptibility to Schistosoma mansoni infection. We have been developing an in vitro model to study the interaction between the snail and the parasite, using tissue-derived cell cultures from Biomphalaria.

METHODS:

The digestive gland- and kidney-derived cells from primary cultures of resistant (B. tenagophila Taim) and susceptible (B. tenagophila HM and B. glabrata BH) strains of Biomphalaria were exposed to S. mansoni sporocysts.

RESULTS:

S. mansoni sporocysts were surrounded and encapsulated exclusively by cells derived from the digestive gland (DG) of B. tenagophila Taim. The process was followed by a marked decrease in the number of free sporocysts in the culture medium. The morphological characteristics of DG-derived cells in culture have been described.

CONCLUSIONS:

Cells derived from DG (but not SK) primary cultures of B. tenagophila Taim may participate in S. mansoni sporocyst control.
Тема - темы
Key words

Полный текст: 1 База данных: LILACS Основная тема: Biomphalaria / Schistosomiasis mansoni Тип исследования: Prognostic_studies Пределы темы: Animals Язык: En Журнал: Jornal brasileiro de medicina tropical / Rev Soc Bras Med Trop / Rev. Soc. Bras. Med. Trop / Rev. Soc. Bras. Med. Trop. (Online) / Revista da Sociedade Brasileira de Medicina Tropical (Impresso) Тематика журнала: MEDICINA TROPICAL Год: 2020 Тип: Article

Полный текст: 1 База данных: LILACS Основная тема: Biomphalaria / Schistosomiasis mansoni Тип исследования: Prognostic_studies Пределы темы: Animals Язык: En Журнал: Jornal brasileiro de medicina tropical / Rev Soc Bras Med Trop / Rev. Soc. Bras. Med. Trop / Rev. Soc. Bras. Med. Trop. (Online) / Revista da Sociedade Brasileira de Medicina Tropical (Impresso) Тематика журнала: MEDICINA TROPICAL Год: 2020 Тип: Article