Type C botulism in dogs from rural properties located in Goiânia, Brazil
Arq. Inst. Biol. (Online)
; 89: e00152021, 2022. graf
Article
в En
| VETINDEX, LILACS
| ID: biblio-1393889
Ответственная библиотека:
BR1942.1
ABSTRACT
Botulism is a disease usually fatal, caused by the ingestion of neurotoxins produced by Clostridium botulinum. In dogs, intoxication is caused by the ingestion of botulinum toxin type C, and animals often recover spontaneously. The present study describes the occurrence of type C botulism in two dogs domiciled on neighboring rural properties in the municipality of Goiânia, state of Goiás, Brazil, probably associated with ingestion of decomposing bovine carcass. Upon clinical evaluation, the dogs were alert in the lateral decubitus position with ascending flaccid paralysis, absence of eyelid reflexes, and reduced muscle tone. Due to their worsening clinical symptoms, the animals died within 12 h and 3 days after supportive treatment. Botulinum toxin type C was identified, in the serum and feces of both dogs, by seroneutralization in mice with homologous monovalent antitoxin. The results of the high-throughput gene sequencing showed that the abundance of C. botulinum in the fecal microbiota of one of the affected dogs was low (0.53%). In this way, the present study highlights the need of sanitary practices related to the appropriate collection and disposal of bovine carcasses in rural areas since they represent a risk factor for the occurrence of botulism in dogs domiciled on rural properties.
Тема - темы
Key words
Полный текст:
1
База данных:
LILACS
Основная тема:
Botulinum Toxins
/
Botulism
/
RNA, Ribosomal, 16S
/
Sequence Analysis, RNA
/
Clostridium botulinum type C
Тип исследования:
Prognostic_studies
/
Risk_factors_studies
Пределы темы:
Animals
Страна как тема:
America do sul
/
Brasil
Язык:
En
Журнал:
Arq. Inst. Biol. (Online)
Год:
2022
Тип:
Article