Demineralized freeze-dried bone allograft with/without i-Platelet-rich fibrin in 3 wall intrabony defects
Braz. j. oral sci
; 23: e240338, 2024. ilus
Article
в En
| LILACS, BBO
| ID: biblio-1537125
Ответственная библиотека:
BR218.1
ABSTRACT
Demineralized freeze-dried bone allograft (DFDBA) contains bone morphogenetic proteins (BMPs), hence is osteoinductive. Autologous platelet concentrates exhibit a higher quantity of growth factors. Both these biomaterials aid in bone regeneration when placed in three-wall intrabony defects. However, their efficacy when used alone and in conjugation is not clear. Aim:
To assess clinical and radiographic efficacy of injectable platelet-rich fibrin (i-PRF) with microsurgical access flap in the treatment of three-wall intrabony defects in chronic periodontitis patients.Methods:
Thirty sites with three-wall intrabony defects were randomly assigned to control and test group by computer generated method. The test group obtained i-PRF mixed with DFDBA while the control group received only DFDBA. Clinical parameters such as site-specific Plaque index (PI), Radiographic intrabony defect depth (IBDD), modified- Sulcular bleeding index (mSBI), Clinical attachment level (CAL), and Probing pocket depth (PPD) were measured at baseline, three and six months.Results:
Intragroup comparison within the control group and test group exhibited statistically highly significant variation of mean PI, mSBI, PPD, CAL, and IBDD score from baseline to 3 months and from 3-6 months (p<0.001). However, intergroup comparison demonstrated no statistically significant variation of mean IBDD at all 3 intervals (p>0.05).Conclusion:
i-PRF combined with DFDBA enhanced the radiographic and clinical parameters as opposed to DFDBA alone. The role of i-PRF is promising in its capacity for easy obtainability and increased potential to aid in regenerationТема - темы
Key words
Полный текст:
1
База данных:
LILACS
Основная тема:
Bone Regeneration
/
Alveolar Bone Loss
/
Chronic Periodontitis
/
Allografts
/
Platelet-Rich Fibrin
Пределы темы:
Adult
/
Female
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Humans
/
Male
Язык:
En
Журнал:
Braz. j. oral sci
Тематика журнала:
ODONTOLOGIA
Год:
2024
Тип:
Article