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Diagnosis and treatment of chronic lymphocytic leukemia: recommendations from the Brazilian Group of Chronic Lymphocytic Leukemia
Rodrigues, Celso Arrais; Gonçalves, Matheus Vescovi; Ikoma, Maura Rosane Valério; Lorand-Metze, Irene; Pereira, André Domingues; Farias, Danielle Leão Cordeiro de; Chauffaille, Maria de Lourdes Lopes Ferrari; Schaffel, Rony; Ribeiro, Eduardo Flávio Oliveira; Rocha, Talita Silveira da; Buccheri, Valeria; Vasconcelos, Yuri; Figueiredo, Vera Lúcia de Piratininga; Chiattone, Carlos Sérgio; Yamamoto, Mihoko.
Affiliation
  • Rodrigues, Celso Arrais; Universidade Federal de São Paulo. São Paulo. BR
  • Gonçalves, Matheus Vescovi; Universidade Federal de São Paulo. São Paulo. BR
  • Ikoma, Maura Rosane Valério; Universidade Federal de São Paulo. São Paulo. BR
  • Lorand-Metze, Irene; Universidade Federal de São Paulo. São Paulo. BR
  • Pereira, André Domingues; Universidade Federal de São Paulo. São Paulo. BR
  • Farias, Danielle Leão Cordeiro de; Universidade Federal de São Paulo. São Paulo. BR
  • Chauffaille, Maria de Lourdes Lopes Ferrari; Universidade Federal de São Paulo. São Paulo. BR
  • Schaffel, Rony; Universidade Federal de São Paulo. São Paulo. BR
  • Ribeiro, Eduardo Flávio Oliveira; Universidade Federal de São Paulo. São Paulo. BR
  • Rocha, Talita Silveira da; Universidade Federal de São Paulo. São Paulo. BR
  • Buccheri, Valeria; Universidade Federal de São Paulo. São Paulo. BR
  • Vasconcelos, Yuri; Universidade Federal de São Paulo. São Paulo. BR
  • Figueiredo, Vera Lúcia de Piratininga; Universidade Federal de São Paulo. São Paulo. BR
  • Chiattone, Carlos Sérgio; Universidade Federal de São Paulo. São Paulo. BR
  • Yamamoto, Mihoko; Universidade Federal de São Paulo. São Paulo. BR
Rev. bras. hematol. hemoter ; Rev. bras. hematol. hemoter;38(4): 346-357, Oct.-Dec. 2016. tab
Article в En | LILACS | ID: biblio-829948
Ответственная библиотека: BR1.1
Локализация: BR408.1
ABSTRACT
ABSTRACT Chronic lymphocytic leukemia is characterized by clonal proliferation and progressive accumulation of B-cell lymphocytes that typically express CD19+, CD5+ and CD23+. The lymphocytes usually infiltrate the bone marrow, peripheral blood, lymph nodes, and spleen. The diagnosis is established by immunophenotyping circulating B-lymphocytes, and prognosis is defined by two staging systems (Rai and Binet) established by physical examination and blood counts, as well as by several biological and genetic markers. In this update, we present the recommendations from the Brazilian Group of Chronic Lymphocytic Leukemia for the diagnosis and treatment of chronic lymphocytic leukemia. The following recommendations are based on an extensive literature review with the aim of contributing to more uniform patient care in Brazil and possibly in other countries with a similar social-economic profile.
Тема - темы
Key words

Полный текст: 1 База данных: LILACS Основная тема: Prognosis / Leukemia, Lymphocytic, Chronic, B-Cell / Immunophenotyping / Cytogenetics / Neoplasm Staging Тип исследования: Diagnostic_studies / Guideline / Prognostic_studies Страна как тема: America do sul / Brasil Язык: En Журнал: Rev. bras. hematol. hemoter / Rev. bras. hematol. hemoter. (Online) / Revista brasileira de hematologia e hemoterapia (Impresso) Тематика журнала: HEMATOLOGIA Год: 2016 Тип: Article

Полный текст: 1 База данных: LILACS Основная тема: Prognosis / Leukemia, Lymphocytic, Chronic, B-Cell / Immunophenotyping / Cytogenetics / Neoplasm Staging Тип исследования: Diagnostic_studies / Guideline / Prognostic_studies Страна как тема: America do sul / Brasil Язык: En Журнал: Rev. bras. hematol. hemoter / Rev. bras. hematol. hemoter. (Online) / Revista brasileira de hematologia e hemoterapia (Impresso) Тематика журнала: HEMATOLOGIA Год: 2016 Тип: Article