Evaluation of the impact of serogroup C meningococcal disease vaccination program in Brazil and its regions: a population-based study, 2001-2013
Mem. Inst. Oswaldo Cruz
;
112(4): 237-246, Apr. 2017. tab, graf
Статья
в английский
| LILACS
| ID: biblio-841785
ABSTRACT
BACKGROUND Meningococcal C conjugate (MenC) vaccine was introduced as part of the Brazilian National Immunisation Program in 2010 for children < 1 year of age. OBJECTIVES The study objective was to evaluate the impact of this vaccination strategy. METHODS An observational, mixed ecological and analytical study was conducted, based on time series panel data from surveillance records (2001-2013). FINDINGS A total of 37,538 of meningococcal disease cases were recorded during the study period. Of these, 19,997 were attributed to serogroup C. A decrease in meningococcal disease serogroup C (MDC) incidence among children aged < 1 year [65.2%; 95% confidence interval (CI) 20.5-84.7%] and 1-4 years (46.9%; 95%CI 14.6-79.1%) were found in the three years following vaccination introduction. Vaccination impact on the reduction of MDC incidence varied from 83.7% (95%CI 51.1-100.0%) in the Midwest region to 56.7% (95%CI 37.4-76.0%) in the Northeast region. MAIN CONCLUSIONS Vaccination against MDC in Brazil had a positive impact on the population of children aged < 1 year, across all regions, and on the 1-4 year-old cohort. Nevertheless, in our view there is scope for improving the vaccination strategy adopted in Brazil.
Полный текст:
Имеется в наличии
База данных:
LILACS - Страны Америки -
Основная тема:
Meningococcal Vaccines
/
Meningitis, Meningococcal
/
Meningococcal Infections
/
Neisseria meningitidis
Тип исследования:
Оценочные исследования
Пределы темы:
Дети
/
Детский дошкольный
/
Женщины
/
Люди
/
Мужчины
Страна как тема:
Южная Америка
/
Бразилия
Язык:
английский
Журнал:
Mem. Inst. Oswaldo Cruz
Тематика журнала:
Тропическая медицина
/
Паразитология
Год:
2017
Тип:
Статья
Аффилированная страна:
Учреждение/Аффилированная страна:
Universidade de Brasília/BR
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