Biomechanical study of the effect of platelet rich plasma on the treatment of medial collateral ligament lesion in rabbits
Acta cir. bras
; 32(10): 827-835, Oct. 2017. graf
Article
в En
| LILACS
| ID: biblio-886173
Ответственная библиотека:
BR1.1
ABSTRACT
Abstract Purpose:
To evaluate the use of platelet-rich plasma in the early stages of healing of traumatic injury of the medial collateral ligament in the knee of rabbits.Methods:
Thirty rabbits were subjected to surgical lesion of the medial collateral ligament. Of these, 16 were treated with platelet-rich plasma and 14 with saline (control). After 3 and 6 weeks of treatment, 50% of the animals from each group were sacrificed, and biomechanical tests were performed on the injured ligament to compare the tensile strength between the two groups.Results:
Platelet-rich plasma significantly increased the tensile strength of the ligament in the groups treated after3 and 6 weeks. In the group treated with platelet-rich plasma vs. saline, the tensile strength values were 3192.5 ± 189.7 g/f vs. 2851.1 ± 193.1 g/f at3 weeks (p = 0.005) and 5915.6 ± 832.0 g/f vs. 4187.6 ± 512.9 g/f at 6 weeks (p = 0.0001).Conclusion:
The use of platelet-rich plasma at the injury site accelerated ligament healing in an animal model, demonstrated by an increase in the tensile strength of the medial collateral ligament.Key words
Полный текст:
1
База данных:
LILACS
Основная тема:
Wound Healing
/
Medial Collateral Ligament, Knee
/
Platelet-Rich Plasma
Тип исследования:
Prognostic_studies
Пределы темы:
Animals
Язык:
En
Журнал:
Acta cir. bras
Тематика журнала:
CIRURGIA GERAL
/
Procedimentos Cir£rgicos Operat¢rios
Год:
2017
Тип:
Article