Immediate postoperative evaluation of enteric anastomosis after the use of meloxicam in rats
Acta cir. bras
; 31(5): 320-326, May 2016. tab, graf
Article
в En
| LILACS
| ID: lil-783801
Ответственная библиотека:
BR1.1
ABSTRACT
ABSTRACT PURPOSE:
To compare ileal anastomoses in the immediate postoperative healing period after meloxicam use.METHODS:
Forty two male Wistar rats were randomly divided into two groups of 21, COX and control group. To COX meloxicam in combination with morphine was given in 3 days period. Control group received only morphine during the same period. Each group was divided into three sub-groups of 7, which were euthanized at 5, 10, and 21 days postoperatively. Comparison was based in histological evaluation of collagen type I and III using sirius red, immunohistochemical through vascular endothelial growth factor and matrix metalloproteinase-9.RESULTS:
Healing process in scheduled periods did not show significant differences (p>0.05) between the COX and control groups during any of the periods.CONCLUSION:
The use of meloxicam in the postoperative period following ileal anastomosis did not affect healing.Key words
Полный текст:
1
База данных:
LILACS
Основная тема:
Thiazines
/
Thiazoles
/
Wound Healing
/
Anti-Inflammatory Agents, Non-Steroidal
/
Cyclooxygenase Inhibitors
/
Ileum
Тип исследования:
Prognostic_studies
Пределы темы:
Animals
Язык:
En
Журнал:
Acta cir. bras
Тематика журнала:
CIRURGIA GERAL
/
Procedimentos Cir£rgicos Operat¢rios
Год:
2016
Тип:
Article