Effect of myosin B on guinea pig muscles--light microscopic and immunological aspects.
Indian J Exp Biol
; 1994 Jun; 32(6): 405-8
Article
в En
| IMSEAR
| ID: sea-60011
ABSTRACT
Experimental myositis was induced in guinea pigs by multiple inoculations with Myosin B fraction of the rabbit skeletal muscle. Quantitative histopathological features were studied and they include necrosis, central nucleation, inflammatory cellular reaction. Besides myositis, features of myocarditis were evident in 40% animals. Circulating immune complexes (CICs) in the sera of experimental animals were isolated by a polyethylene glycol (PEG) precipitation method. Presence of antimyosin B antibody in the immune complexes was characterised by an enzyme-linked immunosorbent assay. The role of circulating immune complexes in pathogenesis of experimental myositis and human polymyositis have been emphasised.
Полный текст:
1
База данных:
IMSEAR
Основная тема:
Male
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Myosins
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Immunization
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Muscle, Skeletal
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Guinea Pigs
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Animals
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Microscopy
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Myositis
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Antigen-Antibody Complex
Язык:
En
Журнал:
Indian J Exp Biol
Год:
1994
Тип:
Article