Progress of researches on molecular mechanisms underlying helminth infection-mediated type 1/2 host immune responses / 中国血吸虫病防治杂志
Chinese Journal of Schistosomiasis Control
; (6): 534-538, 2023.
Article
в Zh
| WPRIM
| ID: wpr-1003614
Ответственная библиотека:
WPRO
ABSTRACT
Helminth infections are widespread worldwide, and pose a serious threat to human health and animal husbandry development. Understanding of helminth-host interactions is critical to effective control and ultimate eradication of helminthiasis. Following host infections, helminth infections firstly initiate innate immune responses and then mediate adaptive immune responses. Type 1 immune responses are predominant at early stage of helminth infections, which mainly play anti-infective actions, and type 2 immune responses are predominant at late stage of infections, which are associated with helminth immune evasion and aggravation of tissue damages. This review summarizes the progress of researches on type 1/2 immune responses-associated signaling pathways mediated by helminth infections in hosts.
Key words
Полный текст:
1
База данных:
WPRIM
Основная тема:
Signal Transduction
/
Helminthiasis
/
Helminths
/
Host-Parasite Interactions
/
Immunity, Innate
Пределы темы:
Animals
/
Humans
Язык:
Zh
Журнал:
Chinese Journal of Schistosomiasis Control
Год:
2023
Тип:
Article