The therapeutic effect of salidroside on rats with permanent cerebral ischemia through regulating PDK/Akt signaling pathway / 中国药理学通报
Chinese Pharmacological Bulletin
; (12): 698-703, 2021.
Article
в Zh
| WPRIM
| ID: wpr-1014421
Ответственная библиотека:
WPRO
ABSTRACT
Aim To investigate the neuroprotective effect and mechanism of salidroside (Sal) on rats with permanent middle cerebral artery occlusion model (pMCAO) by regulating the PI3 K/AKT signaling pathway. Methods A total of 80 healthy adult SPF male SD rats were randomly divided into sham operation group (sham group), model group (pMCAO group), drug administration group (pMCAO + Sal group) and inhibitor group (pMCAO + Sal + YL group). After the pMCAO model rats were prepared by the line bolt method, salidroside (50 mg · kg
Полный текст:
1
База данных:
WPRIM
Язык:
Zh
Журнал:
Chinese Pharmacological Bulletin
Год:
2021
Тип:
Article