Research progress in MRI-based radiomics for predicting the efficacy of transcatheter arterial chemoembolization for hepatocellular carcinoma / 介入放射学杂志

ABSTRACT

Hepatocellular carcinoma(HCC)is the fifth most common malignant tumor in the world and it is characterized by clinically insidious onset and high mortality rate.As a preferred treatment method for patients with moderate and advanced HCC,transcatheter arterial chemoembolization(TACE)has many advantages such as reducing tumor load and relieving patient pain,but the selection of the patients who may get benefits from TACE treatment remains a challenging issue.Therefore,it is essential to predict the efficacy of TACE.At present,various methods including clinical laboratory testing,imaging method,genetic-molecular method,etc.have been used to predict the therapeutic efficacy of TACE.Imaging prediction has the advantages of high visualization and strong interpretability,and MRI functional imaging sequence can better demonstrate the details of the lesion.Radiomics,as an emerging imaging field,can complement or even replace tumor biopsy by quantifying the tumor phenotypic variation.This paper aims to make a review concerning the correlation between the imaging radiomics and the prediction of TACE efficacy in patients with HCC,and to discuss whether MRI imaging radiomics can be used as a valid and reproducible method for predicting TACE efficacy for HCC.(J Intervent Radiol,2024,32:90-94)