Comparison of clinical characteristics between first-episode and relapse of major depressive disorder / 中国心理卫生杂志
Chinese Mental Health Journal
; (12): 25-32, 2024.
Article
в Zh
| WPRIM
| ID: wpr-1025487
Ответственная библиотека:
WPRO
ABSTRACT
Objective:
To describe demographic,clinical and physiological characteristics,treatment between first-episode major depressive disorder(MDD)and relapse MDD,and to explore characteristics of relapse MDD.Methods:
Totally 858 patients who met the diagnostic criteria for depression of the Diagnostic and Statistical Manual of Mental Disorders,Fifth Edition(DSM-5),were included by using the Mini International Neuropsychiatric Interview(MINI),Clinician-Rated Dimensions of Psychosis Symptom Severity,and Hamilton Depression Scale etc.Among them,529(58.6%)were first-episode depression and 329(36.0%)were relapsed.The differences of demographic characteristics,clinical and physiological characteristics,treatment were compared byx2test and Kruskal-Wallis rank sum test.Multivariate logistic regression was used to explore the characteristics of MDD recur-rence.Results:
Compared to first-episode MDD,relapse MDD had more comorbidity(OR=2.11,95%CI1.00-4.44),more days out of role(OR=1.26,95%CI1.01-1.56),more history of using psychiatric drug more than one month(OR=1.41,95%CI1.02-1.97)and electroconvulsive therapy(OR=3.23,95%CI1.42-7.36),and higher waist-hip ratio(OR=33.88,95%CI2.88-399.32).Conclusion:
Relapse MDD has positive as-sociation with comorbidity of mental disorders,out of role,and higher waist-hip ratio.
Полный текст:
1
База данных:
WPRIM
Язык:
Zh
Журнал:
Chinese Mental Health Journal
Год:
2024
Тип:
Article