Individualized intra-arterial thrombolytic therapy in patients with acute cerebral infarction / 中华神经医学杂志

ABSTRACT

Objective To investigate the method, time window, dosage of thrombolytic drug used in different intra-arterial thrombolytic therapies of patients with acute cerebral infarction Methods Sixty patients with acute cerebral infarction within 12 h were chosen in our study; they were treated by different intra-arterial thrombolytic therapies. The therapeutic effect (recanalization) were evaluated through cerebral angiography. Results The complete recanalization rate was 55％ (33/60), partial recanalization rate 38.3％ (23/60) and non-efficiency 6.7％ (4/60). Thirty-eight patients (63.3％) were clinically cured, 10 (16.7％) obviously improved, 9 (15％) partially improved and 3 (5％) invalid; no death was noted. Conclusion Treatment of acute cerebral infarction by different intra-arterial thrombolytic therapies is safe and effective. The cure rate will be improved and the death rate and disability rate will be decreased by setting up first aid system and standard therapeutic measurements.