Recent advance in correlation between cerebral micro-infarct and other imaging markers of cerebral small vessel disease / 中华神经医学杂志

ABSTRACT

Cerebral small vessel disease (CSVD) is a prevalent disease in elder people, which is related to cognitive dysfunction, neuropsychological disorder, motor and gait dysfunction, and urinary incontinence. The imaging markers of CSVD mainly include recent subcortical small infarct, lacuna, white matter hyperintensity, enlarged perivascular space, cerebral micro-bleed, cerebral micro-infarct, and cerebral atrophy. At present, the correlation and interaction of CSVD imaging markers and their synergistic effects on clinical symptoms have gradually become the research focus. This article reviews the correlations of cerebral micro-infarct with other CSVD imaging markers to further clarify the pathogenesis of coexistence of a variety of CSVD imaging markers and guide the prevention and treatment of CSVD.