Analysis of the effect of mechanical thrombectomy for acute anterior circulation ischemic stroke in over-time window / 中风与神经疾病杂志

ABSTRACT

@#Objective　To analyze the therapeutic effect of mechanical thrombectomy (MT) in patients with acute anterior circulation ischemic stroke (AACIS) in over-time window.Methods　From January 2018 to November 2018,40 patients with AACIS treated with MT were enrolled in our hospital.Patients were divided into in-time-window group (onset-treatment time ≤6 h,n=30) and over-time-window group (onset-treatment time>6 h,n=10) according to the time of onset-treatment.The therapeutic effect was evaluated by modified thrombolysis in cerebral infarction (mTICI).The National Institutes of Health Stroke Scale (NIHSS) scores were compared before and after treatment to evaluate the improvement of neurological deficits.The modified Rankin scale (mRs) score,complication rate,and mortality were compared at 90 days postoperatively to assess prognosis.Results　The success rate of patients in the in-time-window group was 83.33%（25/30）,and the success rate of patients in the over-time-window group was 80.00% (16/20).There was no significant difference in the success rate between the two groups (P>0.05).The NIHSS scores at the time of discharge were lower than those at admission (P<0.05).There was no significant difference in NIHSS scores between the two groups (P>0.05).Within 90 days after surgery,no deaths occurred in either group.There was no significant difference in the prognosis rate and complication rate between the two groups (P>0.05).Conclusion　MT can effectively improve the recanalization rate of patients in the treatment of patients with AACIS over-time-window,and has similar short-term and long-term treatment effects as patients in the in-time-window.