Maternal and Neonatal Effects of Substance Abuse during Pregnancy: Our Ten-year Experience
Yonsei Medical Journal
; : 705-713, 2008.
Article
в En
| WPRIM
| ID: wpr-153708
Ответственная библиотека:
WPRO
ABSTRACT
PURPOSE: The aim of the study was to assess perinatal outcome of pregnancy burdened with maternal addiction in comparison with an unselected population from a European transition country. MATERIALS AND METHODS: Data on pregnancies complicated by illicit drug abuse (n = 85) managed during a 10-year period (1997-2007) at Split University Hospital were analyzed. Data on the type of drug, course of gestation and labor, and on perinatal outcome were considered. Data on all non-dependence pregnancies recorded during the study period were used as a control group. RESULTS: During the study period, there were 85 dependence-complicated pregnancies (0.2%). Use of heroin alone during pregnancy was recorded in 51 women (50%), methadone alone in 6 (7%), and a combination of heroin and methadone in 9 (11%). Premature delivery was significantly more common in the group of pregnant addicts (21% vs. 6%); 49% of pregnant addicts were carriers of hepatitis C virus (HCV) and 14% of hepatitis B virus (HBV). Neonatal abstinence syndrome developed in 61 infants (7%) born to addicted mothers. There were 4 cases (4.6%) of early neonatal death; 7 neonates had 5-minute Apgar score < or = 7 (8%); 29 neonates had low birth weight for age (33%); and 7 neonates had congenital anomalies (8%). The risk of various congenital anomalies was 3-fold in the group of children born to addicted mothers. CONCLUSION: Addiction pregnancies present a small but high-risk group according to perinatal outcome. Appropriate obstetric and neonatal care can reduce the rate of complications in these pregnancies and improve perinatal outcome.
Key words
Полный текст:
1
База данных:
WPRIM
Основная тема:
Apgar Score
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Pregnancy Complications
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Pregnancy Complications, Infectious
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Birth Weight
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Neonatal Abstinence Syndrome
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Pregnancy Outcome
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Infant Mortality
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Incidence
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Croatia
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Maternal Exposure
Тип исследования:
Incidence_studies
/
Prognostic_studies
Пределы темы:
Adult
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Female
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Humans
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Newborn
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Pregnancy
Страна как тема:
Europa
Язык:
En
Журнал:
Yonsei Medical Journal
Год:
2008
Тип:
Article