Significant Differences in the Clinicopathological Characteristics and Survival of Gastric Cancer Patients from Two Cancer Centers in China and Korea
Journal of Gastric Cancer
; : 19-28, 2015.
Article
в En
| WPRIM
| ID: wpr-176693
Ответственная библиотека:
WPRO
ABSTRACT
PURPOSE: To compare the clinicopathological data and long-term survival of gastric cancer patients in China and Korea. MATERIALS AND METHODS: Patients who had undergone gastrectomy for gastric cancer between 1998 and 2009 in 2 high-volume institutions in both China (n=1,637) and Korea (n=2,231) were retrospectively evaluated. Clinicopathological variables, overall survival (OS), progression-free survival (PFS), and surgery-related complications were assessed for all patients and compared between the 2 institutions. RESULTS: Chinese patients included in the study were significantly older and had a significantly lower body mass index (BMI) than the Korean patients. Esophagogastric junction tumors were more frequent in Chinese patients. However, the number of patients with stage I gastric cancer, the number of harvested lymph nodes, and the number of total gastrectomies were significantly higher in the Korean population. Korean patients also presented with fewer undifferentiated tumors than Chinese patients. Furthermore, Korean patients had prolonged OS and PFS for stage III cancers only. BMI, tumor-node-metastasis (TNM) stage, tumor invasion, number of positive lymph nodes, and distant metastases were all independent factors affecting OS and PFS. CONCLUSIONS: Although China and Korea are neighboring Asian countries, the clinicopathological characteristics of Chinese patients are significantly different from those of Korean patients. Korean gastric cancer patients had longer OS and PFS than Chinese patients. Influencing factors included TNM stage, tumor invasion, and lymph node metastasis.
Key words
Полный текст:
1
База данных:
WPRIM
Основная тема:
Stomach Neoplasms
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Body Mass Index
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China
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Retrospective Studies
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Disease-Free Survival
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Asian People
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Esophagogastric Junction
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Gastrectomy
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Korea
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Lymph Nodes
Тип исследования:
Observational_studies
Пределы темы:
Humans
Страна как тема:
Asia
Язык:
En
Журнал:
Journal of Gastric Cancer
Год:
2015
Тип:
Article