Identification of origins of marker chromosomes using fluorescence in situ hybridization / 中华医学遗传学杂志
Chinese Journal of Medical Genetics
; (6): 415-419, 2013.
Article
в Zh
| WPRIM
| ID: wpr-237236
Ответственная библиотека:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To assess the value of fluorescence in situ hybridization (FISH) and bacterial artificial chromosome FISH (BAC-FISH) for the diagnosis for patients with marker chromosomes.</p><p><b>METHODS</b>Sixteen patients with marker chromosomes were analyzed with technologies including GTG-banding, Q-banding, multiplex FISH and BAC-FISH.</p><p><b>RESULTS</b>The marker chromosomes in the 16 patients were verified as der(Y) (2 cases), psu dic(Y) (1 case), psu dic(15) (1 case), dic(15) (1 case), del(Y) (1 case), r(X) (5 cases), i(14 or 22) (2 cases), i(18) (1 case).</p><p><b>CONCLUSION</b>FISH and BAC-FISH can both verify the origin of marker chromosomes and provide accurate information for the diagnosis and treatment of patients.</p>
Полный текст:
1
База данных:
WPRIM
Основная тема:
Genetic Markers
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Chromosome Aberrations
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In Situ Hybridization, Fluorescence
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Diagnosis
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Genetics
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Genetic Diseases, Inborn
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Methods
Тип исследования:
Diagnostic_studies
Пределы темы:
Adolescent
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Adult
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Child
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Female
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Humans
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Male
Язык:
Zh
Журнал:
Chinese Journal of Medical Genetics
Год:
2013
Тип:
Article