Clinical and coronary features of systemic lupus erythematosus patients with coronary artery disease / 中华心血管病杂志
Chinese Journal of Cardiology
; (12): 382-385, 2012.
Article
в Zh
| WPRIM
| ID: wpr-275040
Ответственная библиотека:
WPRO
ABSTRACT
<p><b>OBJECTIVES</b>To observe the clinical and coronary features of patients with systemic lupus erythematosus (SLE) and coronary artery disease (CAD).</p><p><b>METHODS</b>Among 2877 SLE inpatients (age ≥ 18 years, male 363, female 2514) admitted in the Peking Union Medical College Hospital between January 1999 to October 2009, 33 patients [mean age (50.7 ± 12.8) years] were diagnosed with CAD and coronary angiogram was available in 20 out of these 33 patients. Clinical and coronary features of these patients were retrospectively reviewed.</p><p><b>RESULTS</b>The incidence of CAD was significantly higher in male SLE patients than in female patients [2.48% (9/363) vs. 0.95% (24/2514), P = 0.022]. Patients with secondary antiphospholipid syndrome were more likely to suffer from CAD [5.76% (8/139) vs. 0.91% (25/2738), P < 0.001]. Myocardial infarction was the major form of CAD (24/33). Coronary artery angiographic changes included coronary stenosis and occlusions, coronary aneurysms and acute thrombosis and multi-vessel lesions was found in 75.0% (15/20) patients with SLE and CAD.</p><p><b>CONCLUSIONS</b>Male SLE patients and patients with secondary antiphospholipid syndrome are at higher risk for CAD. Myocardial infarction and multi-vessel lesions are common in SLE patients with CAD.</p>
Полный текст:
1
База данных:
WPRIM
Основная тема:
Pathology
/
Coronary Artery Disease
/
Risk Factors
/
Coronary Angiography
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Antiphospholipid Syndrome
/
Lupus Erythematosus, Systemic
Тип исследования:
Etiology_studies
/
Risk_factors_studies
Пределы темы:
Adolescent
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Adult
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Aged
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Female
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Humans
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Male
Язык:
Zh
Журнал:
Chinese Journal of Cardiology
Год:
2012
Тип:
Article