Recombination within the human leucocyte antigen / 中华医学遗传学杂志
Chinese Journal of Medical Genetics
; (6): 427-430, 2005.
Article
в Zh
| WPRIM
| ID: wpr-280035
Ответственная библиотека:
WPRO
ABSTRACT
Understanding with greater clearness the characteristics of recombination within the human leucocyte antigen(HLA) is of deep significance to gaining an insight into the evolutionary process of shaping HLA allelic diversity and ultimately the human resistance against diverse pathogens. Family studies and statistical analysis of recombination have provided estimations of recombination fractions across the major histocompatibility complex and have identified the potential recombination hotspots. Other characteristics such as haplotype specificity and sequence motifs have been intensively studied. The recombination fractions, hotspots and other characters are reviewed in this paper.
Полный текст:
1
База данных:
WPRIM
Основная тема:
Recombination, Genetic
/
Haplotypes
/
Linkage Disequilibrium
/
Gene Frequency
/
Genetics
/
HLA Antigens
Тип исследования:
Prognostic_studies
Пределы темы:
Humans
Язык:
Zh
Журнал:
Chinese Journal of Medical Genetics
Год:
2005
Тип:
Article