Research progress of acute coagulopathy of trauma-shock / 中华创伤杂志(英文版)
Chinese Journal of Traumatology
; (6): 95-97, 2015.
Article
в En
| WPRIM
| ID: wpr-316843
Ответственная библиотека:
WPRO
ABSTRACT
Acute coagulopathy of trauma-shock (ACoTS) occurs in 25% of patients with severe trauma in the early phase, and the mortality of those patients is four-fold higher than patients without coagulopathy. The pathophysiology of this complicated phenomenon has been focused on in recent years. Tissue injury and hypoperfusion, activated protein C and Complements play important roles in the early phase after trauma. While the use of blood products, hypothermia, acidosis and inflammation are the main mechanism in late phase. Supplementing coagulation factors and platelets to improve ACoTS are inefficient. Only positive resuscitation from shock and improving tissue hypoperfusion have expected benefits.
Полный текст:
1
База данных:
WPRIM
Основная тема:
Physiology
/
Shock, Traumatic
/
Blood Coagulation Disorders
/
Complement System Proteins
/
Protein C
/
Disseminated Intravascular Coagulation
/
Hypothermia
/
Inflammation
Пределы темы:
Humans
Язык:
En
Журнал:
Chinese Journal of Traumatology
Год:
2015
Тип:
Article