Kidney transplantation improves spermatogenic function in patients with uremia / 中华男科学杂志

ABSTRACT

<p><b>OBJECTIVE</b>To study the changes of testicular spermatogenic function after kidney transplantation.</p><p><b>METHODS</b>Thirty male patients with uremia underwent kidney transplantation. Semen analyses were made and sperm ultrastructural changes were studied before and after the operation.</p><p><b>RESULTS</b>Sperm viability, motility and movement velocity were significantly higher in the postoperative group than in the preoperative group [(70.08 +/- 2.86 vs (36.04 +/- 8.01)], [(76.15 +/- 3.75)% vs (39.27 +/- 4.14)%], [(16.80 +/- 1.11) microm/s vs (8.43 +/- 2.01)] micro/s, respectively (P < 0.01). Sertoli cell, acrosome and mitochondria structures inclined to normal after kidney transplantation.</p><p><b>CONCLUSION</b>Kidney transplantation can significantly improve spermatogenic function in patients with uremia.</p>