Alternatively spliced variants of constitutive androstane receptor in liver of mouse / 浙江大学学报·医学版
Journal of Zhejiang University. Medical sciences
; (6): 113-117, 2008.
Article
в Zh
| WPRIM
| ID: wpr-344366
Ответственная библиотека:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the existence of alternatively spliced variants of constitutive androstane receptor (CAR) in liver of mouse.</p><p><b>METHODS</b>The nucleotide from liver of mouse was purified and the CAR cDNA was amplified by PCR. The fragments of CAR cDNA were cloned to T vector and sequence analysis was performed.</p><p><b>RESULT</b>Various spliced variants of CAR in liver mouse were confirmed by DNA sequencing.</p><p><b>CONCLUSION</b>There are alternatively spliced variants in CAR, which are located in the ligand binding sequence of CAR.</p>
Полный текст:
1
База данных:
WPRIM
Основная тема:
Molecular Sequence Data
/
Amino Acid Sequence
/
Alternative Splicing
/
Receptors, Cytoplasmic and Nuclear
/
DNA, Complementary
/
RNA Splice Sites
/
Genetics
/
Liver
/
Metabolism
Пределы темы:
Animals
Язык:
Zh
Журнал:
Journal of Zhejiang University. Medical sciences
Год:
2008
Тип:
Article