Noninvasive prenatal diagnosis of single gene disorders through cell-free fetal DNA in maternal blood / 中华医学遗传学杂志
Chinese Journal of Medical Genetics
; (6): 410-413, 2009.
Article
в Zh
| WPRIM
| ID: wpr-349065
Ответственная библиотека:
WPRO
ABSTRACT
The discovery of cell-free fetal DNA (cff-DNA) in maternal plasma offered a new way to noninvasive prenatal diagnosis for single gene disorders. In the past decade, many techniques such as real-time PCR, pyrophosphorolysis-activated polymerization, mass spectrum and digital PCR have been developed for noninvasive prenatal diagnosis. In this review, the author discuss the principles, applications, advantages and disadvantages of these techniques.
Полный текст:
1
База данных:
WPRIM
Основная тема:
Prenatal Diagnosis
/
Blood
/
DNA
/
Diagnosis
/
Fetal Diseases
/
Genetics
/
Genetic Diseases, Inborn
/
Maternal-Fetal Exchange
/
Methods
Тип исследования:
Diagnostic_studies
Пределы темы:
Female
/
Humans
/
Pregnancy
Язык:
Zh
Журнал:
Chinese Journal of Medical Genetics
Год:
2009
Тип:
Article