Study on semi-synthetic transforming technology for the natural product of isocorydione / 药学学报
Acta Pharmaceutica Sinica
; (12): 1471-5, 2011.
Article
в Zh
| WPRIM
| ID: wpr-414914
Ответственная библиотека:
WPRO
ABSTRACT
Transforming technology for semi-synthesized isocorydione from the natural product ofisocorydine was studied. The factors affecting on the reaction yield were investigated. UV spectrophotometry was used to indicate the semi-synthesized yield of isocorydione. The optimum reaction conditions were determined as following reacting for 12 h in the solution of sodium dihydrogen phosphate at pH 10, the temperature was 25 degrees C and the ratio of isocorydine to Fremy's radical was 1 2. Under the optimum conditions, the yield could reach up to 50.0%. The molecular structure of isocorydione was elucidated by X-ray single-crystal diffraction analysis for the first time.
Полный текст:
1
База данных:
WPRIM
Язык:
Zh
Журнал:
Acta Pharmaceutica Sinica
Год:
2011
Тип:
Article