Expression of HERG1 and Kv3.4 in oral lichen planus / 实用口腔医学杂志
Journal of Practical Stomatology
; (6): 206-210, 2014.
Article
в Zh
| WPRIM
| ID: wpr-445201
Ответственная библиотека:
WPRO
ABSTRACT
Objective:To investigate the expression of HERG1 and Kv3.4 in normal oral mucosa(NOM)and oral lichen planus (OLP).Methods:20 OLP and 1 6 NOM specimens were collected and immunohistochemically stained(IHC)by SP method for the detection of HERG1 and Kv3.4 protein expression.Results:HERG1 and Kv3.4 were negative or weak-positive in the sapmles of bas-al layer of NOMand non-erosive OLP,but positive in basal layer,spinous layer and granular layer of erosive OLP.The expression of HERG1 and Kv3.4 was higher in OLP than in NOM tissues (P <0.05);and higher in erosive OLP than in non-erosive OLP(P <0.05).In OLP HERG1 expression was positively related to Kv3.4(P <0.05).Conclusion:HERG1 and Kv3.4 may be related to the development of OLP.
Полный текст:
1
База данных:
WPRIM
Язык:
Zh
Журнал:
Journal of Practical Stomatology
Год:
2014
Тип:
Article