Expression of miR-124 and its relationship with E-cadherin and androgen receptor in triple-negative breast cancer / 实用肿瘤学杂志
Practical Oncology Journal
; (6): 97-101, 2017.
Article
в Zh
| WPRIM
| ID: wpr-512056
Ответственная библиотека:
WPRO
ABSTRACT
Objective The objective of this study was to explore the expression of miRNA-124(miR-124)and its correlation with E-cadherin and androgen receptor(AR)in triple-negative breast cancer(TNBC).Methods The expression of miR-124 was detected by RT-PCR in TNBC tissues and adjacent normal breast tissues.The expression of E-cadherin and AR in TNBC was detected by immunohistochemistry.Results The expression of miR-124 in TNBC tissues was significantly correlated with histological grade and the expression of E-cadherin(P0.05).Conclusion In TNBC,miR-124 may play an anti-tumor effect by modulating the expression of E-cadherin.
Полный текст:
1
База данных:
WPRIM
Язык:
Zh
Журнал:
Practical Oncology Journal
Год:
2017
Тип:
Article