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Gadoxetic Acid (Gd-EOB-DTPA)-Enhanced MRI versus Gadobenate Dimeglumine (Gd-BOPTA)-Enhanced MRI for Preoperatively Detecting Hepatocellular Carcinoma: an Initial Experience
Article в En | WPRIM | ID: wpr-65185
Ответственная библиотека: WPRO
ABSTRACT
OBJECTIVE: This study was designed to compare the diagnostic performance of gadoxetic acid-enhanced magnetic resonance imaging (MRI) with gadobenate dimeglumine-enhanced MRI for preoperatively detecting hepatocellular carcinoma (HCC). MATERIALS AND METHODS: Eighteen consecutive patients (17 men and one woman, age range: 31-73 years) with 22 HCCs underwent examinations with gadoxetic acid enhanced MRI and gadobenate dimeglumine-enhanced MRI on a 3.0-Tesla unit. The diagnosis of HCC was established after surgical resection and pathological conformation. Three observers independently reviewed each MR image in a random order on a tumor-by-tumor basis. The diagnostic accuracy of these techniques for the detection of HCC was assessed by performing an alternative free-response receiver operating characteristic (ROC) analysis. The sensitivity and positive predictive values were evaluated. RESULTS: The average value of the area under the ROC curve (Az) for gadoxetic acid enhanced MRI (0.887) was not significantly different from the Az (0.899) for gadobenate dimeglumine-enhanced MRI (p > 0.05). The overall sensitivities of gadoxetic acid enhanced MRI and gadobenate dimeglumine-enhanced MRI were 80% and 83%, respectively, with no significant difference (p > 0.05). The differences of the positive predictive values for the two contrast agents for each observer were not statistically significant (p > 0.05). CONCLUSION: The diagnostic performance of gadoxetic acid-enhanced MRI and gadobenate dimeglumine-enhanced MRI for preoperatively detecting HCC is quite similar.
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Полный текст: 1 База данных: WPRIM Основная тема: Organometallic Compounds / Magnetic Resonance Imaging / Image Interpretation, Computer-Assisted / Predictive Value of Tests / ROC Curve / Sensitivity and Specificity / Carcinoma, Hepatocellular / Statistics, Nonparametric / Gadolinium DTPA / Liver Neoplasms Тип исследования: Diagnostic_studies / Prognostic_studies Пределы темы: Adult / Aged / Female / Humans / Male Язык: En Журнал: Korean Journal of Radiology Год: 2010 Тип: Article
Полный текст: 1 База данных: WPRIM Основная тема: Organometallic Compounds / Magnetic Resonance Imaging / Image Interpretation, Computer-Assisted / Predictive Value of Tests / ROC Curve / Sensitivity and Specificity / Carcinoma, Hepatocellular / Statistics, Nonparametric / Gadolinium DTPA / Liver Neoplasms Тип исследования: Diagnostic_studies / Prognostic_studies Пределы темы: Adult / Aged / Female / Humans / Male Язык: En Журнал: Korean Journal of Radiology Год: 2010 Тип: Article