Diagnostic value of serum procalcitonin and C-Reactive protein in cirrhosis ascites patients with spontaneous peritonitis / 中国生化药物杂志

ABSTRACT

Objective To evaluate the diagnostic value of serum procalcitonin (PCT) and C-Reactive protein(CRP) in cirrhosis patients with spontaneous peritonitis(SBP). Methods 45 cirrhosis patients with SBP(cirrhosis, spontaneous peritonitis group) and 52 cirrhosis patients without SBP(cirrhosis, non peritonitis group) in the department of Gastroenterology, Anji people's Hospital from January 2010 to January 2015 were enrolled, the serum PCT levels of 2 groups were detected by immune luminescence, and the serum CRP levels of 2 groups were detected by latex enhanced turbidimetric immunoassay, then the differences between the two groups were compared. Results Compared with cirrhosis patients without SBP, the PCT and CRP level have significantly increased in cirrhosis patients with SBP, and the sensitivity and specificity of PCT were higher than CRP, also, PCT combined with CRP test was more sensitive and specific than tested alone. Conclusion PCT combined with CRP test have great sensitivity and specificity in the diagnosis of cirrhosis ascites patients with SBP, and can be considered as the early diagnostic indictors of SBP.