IL-6、IL-1? and TNF? induce the expression of c-fos and c -jun in human fetal cere-bral neurons / 中国免疫学杂志
Chinese Journal of Immunology
; (12)1999.
Article
в Zh
| WPRIM
| ID: wpr-674723
Ответственная библиотека:
WPRO
ABSTRACT
Objective:To study the effects of IL 6、IL 1? and TNF? on the expression of c fos and c jun,which may provide the foundation for a further study in clinic.Methods:Used the a model of primary culture of human fetal cerebral neurons in serum free medium,by DNA RNA dot blot hybrdization.Results:The expression of c fos and c jun was increased between 15 min to 30 min after stimulation,reached a maximum at 1 h and declined over the subsequent 1 h.Conclusion:IL 6、IL 1? and TNF ? have induce the expression of c fos and c jun during development of human fetal cerebral neurons in vitro at the level of transcription.
Полный текст:
1
База данных:
WPRIM
Язык:
Zh
Журнал:
Chinese Journal of Immunology
Год:
1999
Тип:
Article