Progress on Detection of Metals Ions by Functional Nucleic Acids Biosensor / 分析化学
Chinese Journal of Analytical Chemistry
; (12): 995-1004, 2018.
Article
в Zh
| WPRIM
| ID: wpr-692341
Ответственная библиотека:
WPRO
ABSTRACT
Functional nucleic acids are natural or artificialnucleic acid sequences with specific functions and special structures. Special metal ions are essential trace elements for human health, but excessive metal ions will be harmful to human health. The functional nucleic acids are widely used in the detection of metal ions because of their advantages such as easy modification, low price, high stability and strong specificity. This review describes the function of functional nucleic acid and metal ions, mainly including cutting type, link type, metal ion-mediated base pairing, click chemical type, conformation change type, and other types. Then, biosensor of functional nucleic acid combined with different signal output is introduced. Finally, the research significance and problems of functional nucleic acid in metal ion detection are discussed, and the future development direction and application prospect of functional nucleic acid biosensor are prospected.
Полный текст:
1
База данных:
WPRIM
Тип исследования:
Diagnostic_studies
Язык:
Zh
Журнал:
Chinese Journal of Analytical Chemistry
Год:
2018
Тип:
Article