A Case of Aggravation of Thyroid Goiter after Treatment with PD-1 Inhibitor for Breast Cancer in Patients with Underlying Hashimoto's Thyroiditis
International Journal of Thyroidology
; : 172-175, 2018.
Article
в Ko
| WPRIM
| ID: wpr-738940
Ответственная библиотека:
WPRO
ABSTRACT
Anti-programmed cell death-1 (PD-1) humanized monoclonal antibody inhibits PD-1 activity by binding to the PD-1 receptor on T-cells and blocking PD-1 ligands and induces immune tolerance of cancer cells. It has been widely used for various kinds of cancer treatment. However, many immune-related adverse events (irAEs) have been reported because it modulates our immune system. In this case study, we reported a case of 42-year-old woman with Hashimoto's thyroiditis who showed rapid aggravation of thyroid goiter and acute hyperventilation syndrome after treatment with PD-1 inhibitor as a neoadjuvant chemotherapy for breast cancer.
Key words
Полный текст:
1
База данных:
WPRIM
Основная тема:
Thyroid Gland
/
Thyroiditis
/
Breast
/
Breast Neoplasms
/
T-Lymphocytes
/
Drug Therapy
/
Programmed Cell Death 1 Receptor
/
Goiter
/
Hyperventilation
/
Immune System
Пределы темы:
Adult
/
Female
/
Humans
Язык:
Ko
Журнал:
International Journal of Thyroidology
Год:
2018
Тип:
Article