Change in the Prevalences and Risk Factors of Atrophic Gastritis and Intestinal Metaplasia in Korea: Multicenter Clinical Trials
The Korean Journal of Helicobacter and Upper Gastrointestinal Research
; : 247-257, 2018.
Article
в Ko
| WPRIM
| ID: wpr-738981
Ответственная библиотека:
WPRO
ABSTRACT
BACKGROUND/AIMS: The aim of this study was to analyze the trend of the prevalences of atrophic gastritis (AG) and intestinal metaplasia (IM) from 2011 to 2016~2017 in Korea. And, the risk factors of AG and IM were compared between 2011 and 2016~2017. MATERIALS AND METHODS: A total of 4,023 subjects in 2011 and 2,506 subjects in 2016~2017 were enrolled. AG and IM were diagnosed on the basis of endoscopic findings. Multivariate analysis was performed for risk factors of AG and IM. Seventeen factors were analyzed. RESULTS: The seroprevalence of Helicobacter pylori decreased from 2011 (59.8%; 2,407/4,023) to 2016~2017 (51.6%; 1,293/2,506; P < 0.001). The prevalence of AG decreased from 2011 to 2016~2017 (P=0.018), but that of IM increased (P < 0.001). The risk factors of AG in 2011 were male sex, old age, H. pylori immuoglobulin G (IgG) positivity, family history of gastric cancer (GC), and high-salt diet. For IM in 2011, the risk factors were male sex, old age, H. pylori IgG positivity, and family history of GC. Risk factors of AG in 2016~2017 were old age, H. pylori IgG positivity, and country of residence. For IM in 2016~2017, the risk factors were male sex, old age, family history of GC, high fasting glucose level (≥126 mg/dL), H. pylori IgG positivity, and low income level. CONCLUSIONS: The difference in prevalence trends of AG and IM between 2016~2017 and 2011 could be the result of the different risk factors of AG and IM, such as decreased prevalence of H. pylori infection.
Key words
Полный текст:
1
База данных:
WPRIM
Основная тема:
Stomach Neoplasms
/
Immunoglobulin G
/
Seroepidemiologic Studies
/
Prevalence
/
Multivariate Analysis
/
Risk Factors
/
Helicobacter pylori
/
Fasting
/
Diet
/
Gastritis, Atrophic
Тип исследования:
Clinical_trials
/
Etiology_studies
/
Prevalence_studies
/
Risk_factors_studies
Пределы темы:
Humans
/
Male
Страна как тема:
Asia
Язык:
Ko
Журнал:
The Korean Journal of Helicobacter and Upper Gastrointestinal Research
Год:
2018
Тип:
Article