Research progress of platelet concentrates in repairing articular cartilage defects / 中华地方病学杂志

ABSTRACT

The incidence of articular cartilage defects is high.Due to limited self-repair ability,it is difficult to complete regenerative repair after injury.Platelet concentrates (PCs) is a kind of blood product obtained after centrifugation and other steps of whole blood with high concentration of platelet as the main component,which includes platelets,white blood cells,various growth factors and fibrinogen,it can promote the repair and regeneration of tissue defects and it has been widely used in orthopedics and sports medicine.PCs have been shown to play a significant role in repairing articular cartilage defects and promoting cartilage regeneration.In this paper,the PCs classification,preparation methods,mechanism of action and its animal and clinical trials in repairing articular cartilage defects are reviewed.