Clinical efficacy of nasal high-frequency ventilation in treatment of neonatal respiratory distress syndrome: a Meta analysis / 中国当代儿科杂志
Chinese Journal of Contemporary Pediatrics
; (12): 897-903, 2018.
Article
в Zh
| WPRIM
| ID: wpr-776697
Ответственная библиотека:
WPRO
ABSTRACT
OBJECTIVE@#To systematically evaluate the clinical efficacy of nasal high-frequency ventilation (nHFV) in the treatment of neonatal respiratory distress syndrome (NRDS).@*METHODS@#A literature search was performed in PubMed, Cochrane Library, EMBase (Ovid), Chinese Biomedical Literature Database, Chinese Journal Full-text Database, Wanfang Data, and Weipu Data to collect the randomized controlled trials (RCTs) that compared the clinical efficacy of nHFV and nasal continuous positive airway pressure (nCPAP) in the treatment of NRDS. A Meta analysis was performed on the included RCTs using Rev Man 5.3 software after data extraction and quality evaluation by Cochrane 5.1.0.@*RESULTS@#A total of 4 RCTs involving 218 patients were included. The Meta analysis showed that compared with the nCPAP group, the nHFV group had a significantly better treatment outcome (RR=1.73, 95%CI: 1.39-2.15, P<0.00001). There were no significant differences in the incidence rates of intraventricular hemorrhage, periventricular leukomalacia, bronchopulmonary dysplasia, necrotizing enterocolitis, pneumothorax and retinopathy of prematurity.@*CONCLUSIONS@#Compared with nCPAP, nHFV has better clinical efficacy in the treatment of NRDS, without increasing the risk of related complications.
Полный текст:
1
База данных:
WPRIM
Основная тема:
Respiratory Distress Syndrome, Newborn
/
Infant, Premature
/
High-Frequency Ventilation
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Intermittent Positive-Pressure Ventilation
/
Treatment Outcome
Тип исследования:
Clinical_trials
/
Systematic_reviews
Пределы темы:
Humans
/
Newborn
Язык:
Zh
Журнал:
Chinese Journal of Contemporary Pediatrics
Год:
2018
Тип:
Article