The role of montelukast in the prevention and treatment of bronchopulmonary dysplasia in premature infants / 国际儿科学杂志
International Journal of Pediatrics
; (6): 619-622, 2021.
Article
в Zh
| WPRIM
| ID: wpr-907290
Ответственная библиотека:
WPRO
ABSTRACT
Bronchopulmonary dysplasia is one of the most common chronic respiratory diseases in premature infants, especially in very low birth weight infants.Lung immaturity, inflammatory injury, oxidative stress and abnormal repair after injury are the important factors.Leukotriene is an inflammatory mediator of 5-lipoxygenase pathway and participates in the occurrence of bronchopulmonary dysplasia.Montelukast, as a leukotriene receptor antagonist, may play a role in the treatment of bronchopulmonary dysplasia through anti-inflammation, anti-oxidation and anti-fibrosis.This article will review the potential mechanism and related clinical researches of montelukast which is used in treating bronchopulmonary dysplasia.
Полный текст:
1
База данных:
WPRIM
Язык:
Zh
Журнал:
International Journal of Pediatrics
Год:
2021
Тип:
Article