Clinical and Cytogenetical Characteristics in Acute Myeloid Leukemia with Myelodysplasia-Related Changes / 中国实验血液学杂志
Journal of Experimental Hematology
; (6): 1757-1762, 2021.
Article
в Zh
| WPRIM
| ID: wpr-922330
Ответственная библиотека:
WPRO
ABSTRACT
OBJECTIVE@#To explore the clinical and cytogenetic characteristics of acute myeloid leukemia with myelodysplasia-related changes (AML-MRC) based on morphology define.@*METHODS@#A total of 180 newly diagnosed acute myeloid leukemia (AML) patients were enrolled and retrospectively analyzed, and marrow cell morphology of 126 patients were re-evaluated. The clinical and cytogenetic characteristics, including ages, sex, WBC count, HGB level, PLT count, blasts percentage, abnormal karyotype detection rate of the patients in AML with multilineage dysplasia (AML-MRC-1), secondary AML from myelodysplastic/ myeloproliferative neoplasms (MDS/MPN) (AML-MRC-2), and AML not otherwise specified (AML-NOS) groups were investigated.@*RESULTS@#There was no significant differences between the patients in three groups in terms of sex, age and platelet count (P=0.898, P=0.365, P=0.853), but AML-MRC-2 group (73.2%) was higher than AML-MRC-1 (60.0%) and AML-NOS (56.4%) in the percentages of patients over 60 years old (P=0.228); there were statistically significant differences on WBC count, HGB level, and blasts percentage (P=0.000, P=0.022, P=0.000, AML-MRC-2
Полный текст:
1
База данных:
WPRIM
Основная тема:
Myelodysplastic Syndromes
/
Leukemia, Myeloid, Acute
/
Retrospective Studies
/
Cytogenetic Analysis
/
Cytogenetics
Тип исследования:
Observational_studies
Пределы темы:
Humans
Язык:
Zh
Журнал:
Journal of Experimental Hematology
Год:
2021
Тип:
Article
Полный текст:
1
База данных:
WPRIM
Основная тема:
Myelodysplastic Syndromes
/
Leukemia, Myeloid, Acute
/
Retrospective Studies
/
Cytogenetic Analysis
/
Cytogenetics
Тип исследования:
Observational_studies
Пределы темы:
Humans
Язык:
Zh
Журнал:
Journal of Experimental Hematology
Год:
2021
Тип:
Article