Effect of antidepressants on thyroid hormone level in adolescent depression with suicidal ideation / 上海预防医学
Shanghai Journal of Preventive Medicine
; (12): 786-790, 2023.
Article
в Zh
| WPRIM
| ID: wpr-997030
Ответственная библиотека:
WPRO
ABSTRACT
ObjectiveTo compare the differences in thyroid hormone levels between adolescents with and without suicidal ideation, and to explore the association between thyroid hormone/suicidal ideation and the antidepressant treatment. MethodsA total of 100 patients were divided into non-suicidal ideation group and suicidal ideation group according to the SIOSS. The levels of thyroid-stimulating hormone (TSH), triiodothyronine (T3), thyroxine (T4), free triiodothyronine (FT3) and free thyroxine (FT4) were compared between the two groups as well as their changes after 6 weeks of antidepressant treatment. ResultsThe levels of FT3, FT4 and T4 in the non-suicidal ideation group were higher than those in the suicidal ideation group. After 6 weeks of antidepressant treatment, the levels of FT3, FT4 and T4 in the suicide ideation group were higher than those before the treatment. The FT3 level in the male non-suicidal ideation group was higher than that in the suicidal ideation group. The levels of FT4 and T4 in the female non-suicidal ideation group were higher than those in the suicidal ideation group (all P<0.05) ConclusionThere are differences in thyroid hormone levels between adolescents with and without suicidal ideation (both with first-episode depression), and patients with suicidal ideation have significant changes after treatment with antidepressants.
Полный текст:
1
База данных:
WPRIM
Язык:
Zh
Журнал:
Shanghai Journal of Preventive Medicine
Год:
2023
Тип:
Article