Fluorescent test accurately predicts leak of ischemic colon anastomosis in rats
Acta cir. bras
; 32(6): 440-448, June 2017. tab, graf
Article
在 En
| LILACS
| ID: biblio-886209
Responsible library:
BR1.1
ABSTRACT
Abstract Purpose:
To investigate if fluorescein fluorescent test can predict dehiscence in a model of ischemic colonic anastomosis in rats.Methods:
This experimental controlled trial randomly assigned 55 rats to four groups. Anastomoses were performed in non-ischemic colon segments (control group) and in ischemic colon segments measuring 1, 2 or 3 cm long (groups 1, 2 and 3, respectively). Fluorescein was injected and the tissues were examined under ultraviolet light. Seven days later, a second-look surgery was performed to check for the presence or absence of anastomosis dehiscence.Results:
Twenty-four rats presented anastomotic dehiscence during the second-look surgery. Reticular and nonfluorescent patterns were significantly associated with the occurrence of anastomotic dehiscence. Fluorescein fluorescence had a sensitivity of 95.8%, specificity of 89.2%, positive predictive value of 88.4%, negative predictive value of 96.2%, and accuracy of 92.3% to predict anastomotic dehiscence.Conclusion:
Fluorescein fluorescent test can accurately predict leak in a model of ischemic colonic anastomosis in rats.Key words
全文:
1
索引:
LILACS
主要主题:
Surgical Wound Dehiscence
/
Anastomosis, Surgical
/
Colon
/
Fluorescein
/
Fluorescent Dyes
/
Ischemia
研究类型:
Prognostic_studies
/
Risk_factors_studies
限制:
Animals
语言:
En
期刊:
Acta cir. bras
期刊主题:
CIRURGIA GERAL
/
Procedimentos Cir£rgicos Operat¢rios
年:
2017
类型:
Article