[Anticonvulsant effect of hydroalcoholic extract of Scrophularia striata Boiss. on pentylenetetrazol-induced seizure in mice]

ABSTRACT

Background and Aims: Epilepsy is a central nervous system disorder that appears as sudden convulsions, and transient, repetitive and unpredictable movment, with sensory-motor and autonomic sources. Nowadays, patients with epilepsy use various types of chemical drugs which turn out side effects and cause drug resistance in long-term use. Ease of using herbal plants and their public acceptance have provided them appropriate for pharmacological purposes. Scrophularia striata Boiss., plant grows in areas of Ilam in Iran, has been experimentally used in the treatment of various diseases. In this experiment, the effect of hydroalcoholic extract of this plant was studied on pentylenetetrazol-induced seizures