Western blot seroindeterminate individuals for Human T-lymphotropic Virus 1/2 (HTLV-1/2) in Fortaleza (Brazil): a serological and molecular diagnostic and epidemiological approach
Braz. j. infect. dis
; 7(3): 202-209, Jun. 2003. tab
Article
在 En
| LILACS
| ID: lil-351498
Responsible library:
BR1.1
RESUMO
How to handle Western blot (WB) seroindeterminate individuals for Human T-lymphotropic Virus 1/2 (HTLV-1/2) constitutes a challenge for blood banks and fam ilies. We made a cross-sectional study of 191 enzyme linked immunoassay (EIA) reactive individuals from the hematological center (HEMOCE) of Fortaleza (Brazil), examining their serological (WB) and molecular (PCR) diagnosis, and demographic profiles, as well as a possible association of their condition with other infectious pathologies and risk factors. Ethical institutional approval and personal consent were obtained. Out of 191 EIA reactive individuals, 118 were WB seroindeterminate and 73 were seropositive for HTLV-1/2. In the PCR analysis of 41 WB seroindeterminate individuals, 9 (22 percent) were positive and 32 (78 percent) were negative for HTLV-1/2. The demographic analysis indicated a trend towards a predominance of males among the seroindeterminate individuals and females in the seropositive ones. The seroindeterminate individuals were younger than the seropositive ones. We did not find any association of these conditions with syphilis, Chagas disease or HIV or hepatitis, and with risk factors such as breast-feeding, blood transfusion, STD (syphilis) and IDU
全文:
1
索引:
LILACS
主要主题:
HTLV-I Infections
/
HTLV-II Infections
/
DNA Primers
研究类型:
Diagnostic_studies
/
Etiology_studies
/
Observational_studies
/
Prevalence_studies
/
Risk_factors_studies
限制:
Female
/
Humans
/
Male
国家/地区名称主题:
America do sul
/
Brasil
语言:
En
期刊:
Braz. j. infect. dis
期刊主题:
DOENCAS TRANSMISSIVEIS
年:
2003
类型:
Article