Structural changes of dilated pelvic ureters in adults
Acta cir. bras
; 29(supl.3): 49-54, 2014. tab, graf
Article
在 En
| LILACS
| ID: lil-726243
Responsible library:
BR1.1
ABSTRACT
PURPOSE:
To perform a quantitative assessment of different types of pelvic ureter tissues with chronic dilation in adults, using stereological methods.METHODS:
We analyzed fragments of dilated pelvic ureters obtained from 6 patients aged between 35 and 67 years (mean, 46 years) who underwent ureteral reimplantation surgery for different reasons. The obstruction duration ranged from 27 to 180 days (mean, 93 days). The control group included fragments of normal pelvic ureters obtained during nephrectomy in 7 kidney transplant donors (age range, 25-51 years; mean, 36 years). The volumetric density of collagen in the ureter, elastic fibers, and smooth muscle fibers was assessed.RESULTS:
The volumetric density (Vv) of collagen showed no significant difference between the two groups (control 45.3 ± 6.1; dilated 40.8 ± 6.9; P = 0.23). A statistically significant increase in Vv of elastic fibers was observed in the dilated ureters (control 18.4 ± 1.2; dilated 24.6 ± 5.4; P = 0.03). A statistically significant increase in the Vv of smooth muscle fibers was observed in the dilated ureter (control 42.0 ± 6.0; dilated 56.2 ± 6.1; P = 0.001).CONCLUSION:
The chronically dilated pelvic ureters had significantly more elastin and smooth muscle contents than the controls. .Key words